About
Katja Scheffler is an Associate Professor at INB and leads the Trønderbrain project at the Department of Neurology, St. Olavs Hospital, focusing on next-generation translational medicine approaches in AD research. Her work bridges basic research and clinical applications.
Research Interests
- Translational medicine
- Brain organoids
- Genome regulation
- Treatment development
Selected Publications
- Egiazarian, M.A., Abentung, A., Sakshaug, T.S., Karabeika, E.E., Hanumaihgari, P.R., Grøntvedt, G.R., Sando, S.B., Bjørås, M., Scheffler, K., 2024. The role of impaired oxidative base lesion repair in Alzheimer’s disease. Alzheimer’s & Dementia 20, e090686. https://doi.org/10.1002/alz.090686
- Grøntvedt, G.R., Sando, S.B., Lauridsen, C., Bråthen, G., White, L.R., Salvesen, Ø., Aarsland, D., Hessen, E., Fladby, T., Waterloo, K., Scheffler, K., 2022. Association of Klotho Protein Levels and KL-VS Heterozygosity With Alzheimer Disease and Amyloid and Tau Burden. JAMA Netw Open 5, e2243232. https://doi.org/10.1001/jamanetworkopen.2022.43232
- Obermann, T., Sakshaug, T., Kanagaraj, V.V., Abentung, A., Sousa, M.M.L.D., Hagen, L., Sarno, A., Bjørås, M., Scheffler, K., 2025. Genomic 8-oxoguanine modulates gene transcription independent of its repair by DNA glycosylases OGG1 and MUTYH. Redox Biology 79, 103461. https://doi.org/10.1016/j.redox.2024.103461