About
Prof. Heikki Tanila is a neuroscientist at the University of Eastern Finland, specializing in the relationship between neuronal hyperexcitability and Alzheimer’s disease. His research investigates the complex feedback loops in AD pathogenesis.
Research Interests
- Neuronal hyperexcitability in AD
- Circuit dysfunction in neurodegeneration
- Memory system organization
- Therapeutic interventions
Selected Publications
- Jin, N., Gureviciene, I., Atalay, A.N., Häkli, S., Ziyatdinova, S., Tanila, H., 2022. Preclinical evaluation of drug treatment options for sleep‐related epileptiform spiking in Alzheimer’s disease. A&D Transl Res & Clin Interv 8, e12291. https://doi.org/10.1002/trc2.12291
- Kamondi, A., Grigg-Damberger, M., Löscher, W., Tanila, H., Horvath, A.A., 2024. Epilepsy and epileptiform activity in late-onset Alzheimer disease: clinical and pathophysiological advances, gaps and conundrums. Nat Rev Neurol 20, 162–182. https://doi.org/10.1038/s41582-024-00932-4
- Mabrouk, R., Miettinen, P.O., Tanila, H., 2023. Most dystrophic neurites in the common 5xFAD Alzheimer mouse model originate from axon terminals. Neurobiology of Disease 182, 106150. https://doi.org/10.1016/j.nbd.2023.106150